Would you consider remdesivir and or monoclonal antibodes?
Both approved for treatment and have had good results in both trials and real world use. (i guess trials are techncially also in the real world)
I think they are both approved by MHRA aswell.
Yes but probably in the uk their use would be restricted to the worst cases in hospital, we're just abt to use the antibodies whereas T.rump was treated with them nearly a year ago, so it's all a bit disappointing. Not sure if it's cost or safety issues for the slow rollout.
The safety profile of this drug is well established, I assume it's low cost, and it prevents the viral replication, sounds like a GP could prescribe it in the early stages unlike the two you mentioned.
NHS guidance on remdesivir:
Patients are eligible for treatment with remdesivir, the patient characteristics are:
Hospitalised with coronavirus disease 2019
With pneumonia requiring low-flow supplemental oxygen...
Yet
Remdesivir should not be initiated in patients who present to hospital and are unlikely to survive (determined by clinical judgment). The 4C Mortality Score might be helpful in this assessment.
Remdesivir should not be initiated in patients who present to hospital more than 10 days after symptom onset
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I'm no medical expert but assume initial covid symtoms to pneumonia takes a while, so they're rationing it using these requirements, a full 5 day course is £1,900